Fig. 8: Potential applications of HK model 2. | Communications Biology

Fig. 8: Potential applications of HK model 2.

From: Transformer-based deep learning for accurate detection of multiple base modifications using single molecule real-time sequencing

Fig. 8

A HCC methylation scores were determined by HK model 2 in healthy individuals (n = 15), HBV carriers (n = 13), and HCC patients (n = 13) using sequenced DNA molecules with 1 to 6 CpG sites. B ROC curves of using HCC methylation score for classifying individuals with and without HCC based on molecules with 1 to 6 CpG sites or at least 7 CpG sites. C The jaggedness profile of plasma DNA in a healthy individual. D Patterns of 6mA levels in genomic sites relative to CTCF binding sites.

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