Fig. 5: Far-UV CD spectra of the candidate aptamers.

a All selected aptamers, and b focus on the aptamers exhibiting a characteristic parallel G-quadruplex (G4) profile. Data were obtained at 20 °C in B/W buffer, with aptamer concentrations of approximately 5 µM. Vertical lines positioned at 240 nm and 260 nm define the spectral regions typical of parallel G4 structures.