Fig. 8: Niche construction - angiogenesis.
From: Parallel and convergent dynamics in the evolution of primary breast and lung adenocarcinomas
In the left panels, expression of each gene in normal breast (x-axis) and normal lung (y-axis) is plotted. In the right panels, the expression of each gene in breast cancer (x-axis) and lung cancer (y-axis) is plotted. Both cancers increase the expression of some VEGF family members that promote angiogenesis while other members of the family as well as angiopoietin genes that promote lymphangiogenesis or vascular maturation are downregulated. The overall selection forces result in relative convergence of expression in LUAD and BRCA.
