Fig. 7: TAT-CRE induced lung tumors harbored an increased fraction of VEGFR2 positive macrophages compared to AD-CRE induced lung tumors. | Communications Biology

Fig. 7: TAT-CRE induced lung tumors harbored an increased fraction of VEGFR2 positive macrophages compared to AD-CRE induced lung tumors.

From: TAT-CRE inhalation enables tumor induction corresponding to adenoviral Cre-recombinase in a lung cancer mouse model

Fig. 7

Lung adenocarcinomas induced by TAT-CRE (n = 4, 2 males, 2 females) and AD-CRE (n = 4, 2 males, 2 females) inhalation were analyzed by flow cytometry. a Representative histograms, dot plots and the gating of CD45, CD11c, CD11b, F4/80 and VEGFR2 stains. b F4/80 was analyzed to determine the macrophage rate in the CD11+/CD11b+ immune cell population. c VEGFR2 was analyzed as a pro-angiogenic marker on macrophages. p-values were calculated using an unpaired two sided t-test. Data is shown as mean ± SD. P-values ≤ 0.05 are considered as significant.

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