Fig. 5: Impact of interfering with LAPTM4A on the progression of Glioma. | Communications Biology

Fig. 5: Impact of interfering with LAPTM4A on the progression of Glioma.

From: Loss of LAPTM4A inhibits M2 polarization of tumor-associated macrophages in glioblastoma, promoting immune activation and enhancing anti-PD1 therapy

Fig. 5

A Diagram of the process of stimulating TAM formation by infecting macrophages with sh-LAPTM4A using the supernatant of tumor cell stimulation; B BrdU detection of glioma cell proliferation capability (Scale Bar = 25 μm); C CCK-8 detection of cell viability; D, E Transwell detection of cell migration and invasion capability (Scale Bar = 50 μm); F Immunofluorescence detection of epithelial-to-mesenchymal transition-associated gene expression, N-cadherin, and E-cadherin. N-cadherin or E-cadherin is labeled with green fluorescence, and DAPI is labeled with blue fluorescence (Scale Bar = 25 μm). *P < 0.05, cell experiments were repeated at least three times.

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