Fig. 8: Lack of LAPTM4A mediates anti-tumor immunity in Glioma. | Communications Biology

Fig. 8: Lack of LAPTM4A mediates anti-tumor immunity in Glioma.

From: Loss of LAPTM4A inhibits M2 polarization of tumor-associated macrophages in glioblastoma, promoting immune activation and enhancing anti-PD1 therapy

Fig. 8

A Immunofluorescence detection of CD8α expression in glioma tissues, Scale Bar = 25 µm; B Fluorescence images of tumor size in mice treated with α-PD1; C Flow cytometry detection of CD4+ and CD8+ T cell content in glioma tissues; D Flow cytometry analysis of IFN-γ or TNF-α expression in CD8+ T cells in glioma tissues. n = 10, *P < 0.05, ns indicates no difference.

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