Fig. 8: CV and PPR analysis during STDP expression.
From: Coincidence detection between apical and basal dendrites drives STDP in cerebellar Golgi cells
A Individual EPSCs (60 sweeps) evoked by PP stimulation of mf before (con) and 30 min after (ind) STDP induction are shown superimposed (thin traces) along with their respective averages (thick traces). The plots show the time course of average EPSC changes (large dots), with individual recordings overlaid (small dots). The arrows indicate the STDP induction time. Note that the magnitude of both st-LTD (orange dots) and st-LTP (purple dots) was similar to that obtained with SP stimulation (orange and purple dashed lines, replotted from Fig. 1B; SP, st-LTD: n = 6, N = 6, vs. PP, st-LTD: n = 5, N = 5, p = 0.91; SP, st-LTP: n = 6, N = 5, vs. PP, st-LTP: n = 5, N = 4, p = 0.58; mean ± SEM; Student’s unpaired t-test; some standard errors are small and fall inside the dots). B Time course of PPR and CV changes after STDP induction (large dots), with individual recordings overlaid (small dots; PPR, st-LTD: n = 5, N = 5, p = 0.59; PPR st-LTP: n = 5, N = 4, p = 0.52; CV, st-LTD: n = 5, N = 5, p = 0.85; CV, st-LTP: n = 5, N = 4, p = 0.55; mean ± SEM; Student’s paired t test; some standard errors are small and fall inside the dots). The arrows indicate the STDP induction time. Right, bar graphs show the average PPR and CV changes for Δt = −25 ms (orange) and Δt = +25 ms (purple).
