Table 1 The accuracy of the alignment was measured using two different Dice scores

From: Brainbuilder: a software pipeline for 3D reconstruction of cortical maps from multi-modal 2D data sets

   

Human

   

Macaque

Slab

1 (Anterior Pole)

2

3

4

5

6 (Posterior Pole)

Whole Brain

Inter-section Dice Score

0.94 ± 0.04

0.93 ± 0.05

0.89 ± 0.07

0.92 ± 0.04

0.93 ± 0.06

0.94 ± 0.06

0.90 ± 0.1

Section to Reference Dice Score

0.96 ± 0.06

0.94 ± 0.03

0.93 ± 0.04

0.93 ± 0.04

0.95 ± 0.05

0.95 ± 0.02

0.93 ± 0.08

  1. The Dice score of the non-linearly aligned section versus the corresponding reference section from the structural volume (“Reference”) and the Dice score between a given section and its immediate neighbors (“Inter-section”). Both Dice scores were consistently high across all tissue slabs and in both human and macaque reconstructions. In the multi-slab human reconstruction, the middle slabs had slightly lower Dice scores (0.89–0.92) versus at the poles. These lower scores likely reflecting both the added difficulty of identifying the anterior and posterior bounds of these slabs on the reference volume and the more varied set of morphological features in these middle slabs (e.g., basal ganglia and temporal lobe).
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