Fig. 1: Time course of M.tb interaction with HAMs and intracellular growth over 72 h.

A Schematic of M.tb cell attachment and uptake, adaptation, and growth in HAMs. B Changes in normalized RLU values over the course of M.tb infection. The RLUs represent mostly uptake and adaptation at 2 h and 24 h, and growth at 48 h and 72 h (see Supplementary Table 1; results shown here are with bacterial MOI of 2:1).