Fig. 5: Expression of IDO1 compared to IL1B and other co-expressed genes in HAMs infected with M.tb at 24 or 72 h. | Communications Biology

Fig. 5: Expression of IDO1 compared to IL1B and other co-expressed genes in HAMs infected with M.tb at 24 or 72 h.

From: Human alveolar macrophage response to Mycobacterium tuberculosis: immune characteristics underlying large inter-individual variability

Fig. 5

A Expression of IDO1 compared to IL1B at 72 h: both are variably expressed with a similar pattern across the 28 HAMs (R2 = 0.81). B–H Select mRNA transcripts with co-expression patterns highly correlated with IDO1 at 24 h (R2 ≥ 0.80). IDO1 is expressed in all HAMs over a wide range of scales in reads per million (RPM), with examples of the most tightly co-expressed genes with IDO1 representing the most variably expressed gene cluster (B–H). Gene expressions are shown in RPM on both axes.

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