Fig. 4: Parallel amino acid site substitutions in the IGSF22 gene of two high-altitude Vulpes species.

A Differential genomic loci of the IGSF22 gene between two high-altitude Vulpes species and their closely relatives. B The alterations in hydrophilicity and hydrophobicity of the protein encoded by the IGSF22S132F genotype. C Protein 3D structure prediction outcomes for IGSF22 gene variants.