Fig. 1: LTP-induced changes in actin dynamics and spine volume decay quickly.

A Schematic of model components and relevant variables. B Example spine shapes from simulation. Colors indicate the curvature: blues for concave and reds for convex regions. C Normalized time-dependent rates of actin dynamics (upper scale bar applies for nucleation only). D Total number of barbed ends depicted as mean (solid curves) and standard deviation (shaded area) over 20 instances of the model. Red curves correspond to the model with LTP-induced changes from (A) and grey curves to a model without (E) Same for spine volume.