Fig. 5: Integrated insights of genetic interpretation and epidemiological results. | Communications Biology

Fig. 5: Integrated insights of genetic interpretation and epidemiological results.

From: Intricate interactions between fine-scale genetic structure, lifestyle, and dietary habits in the Japanese population

Fig. 5

a The Circos plot illustrates the Gene Set Enrichment Analysis (GSEA) results across the four identified clusters, using negative log-transformed P values. The lower circle of the plot represents each of the four clusters. The upper circle highlights the specific gene sets that are unique to each cluster, as determined by their non-overlapping presence in the GWAS Catalog. b A forest plot presents the outcomes of the multinomial logistic regression analysis. The model was adjusted for age, sex, and BMI for each exposure variable. The plot uses vertical lines on the y-axis to represent different lifestyle or dietary variables, with horizontal lines showing ORs and their 95% CIs. Points of intersection with the vertical line at OR = 1.0 suggest no effect. The figure only includes lifestyle or dietary variables with statistically significant relationships (P < 0.05).

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