Fig. 6: Differentially expressed proteins in monocytes upon PNAG treatment. | Communications Biology

Fig. 6: Differentially expressed proteins in monocytes upon PNAG treatment.

From: Staphylococcus aureus biofilm-associated component PNAG stimulates the secretion of the immunomodulatory chemokine CXCL10 via Dectin-1 signaling

Fig. 6

A Volcano plot (-logq versus logFC) showing the difference in the abundance of secreted proteins in monocytes exposed to PNAG. Proteins with significantly differential secretion expressed as q values < 0.05 (indicated by the horizontal red line) and twofold higher (logFC > 1, red) or lower (logFC < -1 blue) secretion (indicated by the vertical red lines) are highlighted. B Gene-Concept network plot of proteins differentially secreted by monocytes upon exposure to PNAG. The gene-concept network was constructed to visualize the most relevant nodes engaging in hubs. Edges confidence correlates with the strength of the PPI. Abbreviations: PNAG: poly N-acetylglucosamine, SpA: S. aureus virulence protein A.

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