Fig. 2: Performance of control and 3xTgAD mice on the 4-Choice Gambling Task. | Communications Biology

Fig. 2: Performance of control and 3xTgAD mice on the 4-Choice Gambling Task.

From: Executive dysfunction is associated with altered hippocampal-prefrontal functional connectivity in 3xTg Alzheimer’s model mice

Fig. 2

a Average choice % of control mice by session. b The same data as for a, but with sessions displayed in blocks of 4. c Average choice % of control mice for advantageous (P1 + P2) versus disadvantageous (P3 + P4) options, by session block. d Average choice % of 3xTg mice by session. e The same data as for d, but with sessions displayed in blocks of 4. f Average choice % of 3xTg mice for advantageous (P1 + P2) versus disadvantageous (P3 + P4) options, by session block. g Net advantageous choice % by individual session. This was calculated by subtracting the average % of disadvantageous choices (P3 + P4) from the average % of advantageous choices (P1 + P2) selected by mice across the session. The higher the value, the better the decision-making and task performance. Control mice had a significantly higher net advantageous choice % than 3xTg mice. h The same data as for g, but with sessions blocked. Control mice had a significantly higher net advantageous choice % than 3xTg mice. n = 5 controls, n = 7 3xTgs. Error bars indicate SEM.

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