Fig. 1: STRaM for cell lines and cell-based therapies. | Communications Biology

Fig. 1: STRaM for cell lines and cell-based therapies.

From: STRaM: A genetic framework for improved cell product provenance for research and clinical translations

Fig. 1

A Overall schematics of STRaM. B An error-sensing bioinformatic pipeline containing 3 analysis modules: STR analysis, STR flanking analysis and EMS analysis. C A New STRaM marker set with STR loci derived from autosomes 1-22. The amelogenin gene is used to distinguish X/Y sex chromosomes. D New assessment criteria defined by 3 indices: SI, PI and EMI for handling identity, purity and editing/mutation tests, respectively.

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