Fig. 4: Subacute distribution and excretion of Pd-NPs in healthy and DSS mice.
From: Biodistribution of nanoplastics in mice: advancing analytical techniques using metal-doped plastics
a XFI-maps showing the Pd content in the mouse droppings collected over 24 h after Pd-NPs gavage on day 9 (content from 3 mice, recovery of Pd correlates to 104% of the daily dose). b Absolute Pd masses in excreted feces (recalculated as % daily dose/mouse) measured with ICP-MS (green) and XFI (blue). Mice that did not receive Pd-NPs gavage (untreated control) are displayed in red. c IMC tissue image of liver showing 104Pd, 105Pd, 106Pd, 108Pd, 110Pd in yellow and DNA in blue for the liver sample from Pd-NPs+DSS (mouse #28334). d IMC dual counts of 108Pd in the colon, small intestine, liver, and kidney for the 3 treatments (untreated control, NP, and Pd-NPs+DSS) (L Liver, K Kidney, C Colon, SI Small Intestine) in 3 mice (untreated control = mouse #28328, Pd-NPs = mouse #28337, Pd-NPs+DSS = mouse #28334). The grey box between 0 and 1 dual counts indicates the noise range of the detector and only pixels above that area contain Pd. Respective ROI images are shown in Fig. S3.
