Fig. 6: ILC in mouse brain exhibits NK and ILC3 subpopulations associated with meningitis. | Communications Biology

Fig. 6: ILC in mouse brain exhibits NK and ILC3 subpopulations associated with meningitis.

From: A single-cell atlas of mouse central nervous system immune cells reveals unique infection-stage immune signatures during the progression of meningitis caused by Streptococcus suis

Fig. 6

A The t-SNE map shows the cluster partitions. B Phenotypic heatmap shows the phenotypic characteristics of the 13 clusters. The cluster frequency heatmap shows their distribution and the Spearman clustering according to the cell proportion in each sample. C t-SNE plots of ILCs from the brain samples of five groups are shown. D, F t-SNE maps showing the expression of specific marker molecules in ILCs. E, G The proportion of specific subgroups in ILCs. N = 4. Error bars represent the median ± SEM. A one-way ANOVA or Dunnett’s test was performed for analysis of multiple groups. P value < 0.05 (*); p < 0.01 (**); p < 0.001 (***); NS no significant difference.

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