Fig. 4: uORF expression in the DG. | Communications Biology

Fig. 4: uORF expression in the DG.

From: Transcriptome-wide mapping of small ribosomal subunits elucidates scanning mechanisms of translation initiation in the mammalian brain

Fig. 4

a Illustration explaining the role of uORFs on the translation of downstream CDS. b Comparison of CDS translation efficiency (TE) in relation to the presence or absence of active uORFs in DG (FPKM-based, t-test statistics). c Illustration explaining the role of uORFs on the scanning efficiency (SE) of downstream CDS. d Comparison of the SE in relation to the presence or absence of active uORFs in DG (FPKM-based, t-test statistics). e Illustration explaining the role of uORFs on the SSU poising over 5′ leaders. f Comparison of the poised SSUs in relation to the presence or absence of active uORFs in DG (FPKM-based, t-test statistics).

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