Fig. 6: Translation landscape of neuropil and soma-enriched transcripts. | Communications Biology

Fig. 6: Translation landscape of neuropil and soma-enriched transcripts.

From: Transcriptome-wide mapping of small ribosomal subunits elucidates scanning mechanisms of translation initiation in the mammalian brain

Fig. 6

a Representation of neuronal compartments (soma and neuropil) with polysomal translation (multiple ribosomes elongating simultaneously) and of monosomal translation (only one ribosome elongating on the transcript). Numbers in parentheses indicate the number of genes used for analysis. b Metagene coverage for transcripts enriched in the soma and preferring monosomal or polysomal translation. c Metagene coverage for transcripts enriched in the neuropil and preferring monosomal or polysomal translation. d Log2 TE (FPKM based, t-test statistics) for neuropil-enriched transcripts between the transcripts preferring monosomal or polysomal translation in the DG. e Log2 SE (FPKM based, t-test statistics) for neuropil-enriched transcripts between the transcripts preferring monosomal or polysomal translation in the DG. f Log2 Initiation Rate (FPKM-based, t-test statistics) for neuropil-enriched transcripts between the transcripts preferring monosomal or polysomal translation in the DG.

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