Fig. 1: ConSTRain performance on Q100 benchmark. | Communications Biology

Fig. 1: ConSTRain performance on Q100 benchmark.

From: Genotyping short tandem repeats across copy number alterations, aneuploidies, and polyploid organisms

Fig. 1

A Distribution of normalised sequencing depth observed by ConSTRain across 167114 repeat loci in the 100X HG002 WGS sample. The x-axis shows the sequencing depth normalised by the copy number of repeat loci. The left y-axis shows the accuracy of allele length calls (blue line and dots). The right y-axis shows the proportion of loci (grey histogram). Note: only normalised depth values between 0 and 60 are shown for visual clarity. B Accuracy of unfiltered and filtered ConSTRain STR allele length calls for 100X WGS of HG002, as well as for the same sample downsampled to 30X and 10X depth of coverage. Note: y-axis starts at 0.75.

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