Fig. 2: Effects of tizoxanide on bacterial growth and T3SS gene expression. | Communications Biology

Fig. 2: Effects of tizoxanide on bacterial growth and T3SS gene expression.

From: Tizoxanide associated with anti-virulent activity controls fire blight disease caused by Erwinia amylovora in Malus asiatica

Fig. 2

a Chemical structure of tizoxanide. b Growth of E. amylovora TS3128 in LB medium at 28 °C following treatment with various concentrations of tizoxanide. c Effects of tizoxanide on the hrpA promoter activity. Images were captured 18 h after treatment with tizoxanide. Scale bar, 40 µm. d Relative expression of T3SS-related genes in E. amylovora TS3128 treated with different concentrations of tizoxanide. Total RNA was isolated from the E. amylovora TS3128 grown in HMM medium supplemented with tizoxanide for 18 h. ns, not significantly different; *, P < 0.05; **, P < 0.01; and ***, P < 0.001 based on Student’s t-test.

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