Fig. 1: Overview of DynaRNA architecture.
From: DynaRNA: accurate dynamic RNA conformation ensemble generation with diffusion model
A The framework of DynaRNA comprises two processes: a forward noising process indicated by the blue solid line, in which Gaussian noise is progressively added to the input structure, and a reverse denoising process indicated by the green dashed line. B Distribution of adjacent C4’ distances of conformation ensembles generated by DynaRNA(blue) compared to PDB experimental structures(orange). C EGNNs are utilized to predict the noise and denoise. D Distribution of C4’ hyper bond angles of conformation ensembles generated by DynaRNA (blue) compared to PDB experimental structures (green).
