Fig. 6: Comparison of effects of unilateral activation of CaMKIIa-RNs located in MdV-IRt area and in two adjacent areas. | Communications Biology

Fig. 6: Comparison of effects of unilateral activation of CaMKIIa-RNs located in MdV-IRt area and in two adjacent areas.

From: Role of CaMKIIa reticular neurons of caudal medulla in control of posture

Fig. 6

A, D A scheme of the sagittal section of the brainstem indicating the location of two areas (the gigantocellular nucleus, Gi, and the area that is dorsal to MdV, d-MdV) adjacent to MdV-IRt area. B, E Representative examples of unilateral infection of CaMKIIa-RNs in Gi (B) and in d-MdV (E) with AAV-CaMKIIa-hM3Dq-mCherry. C, F Heatmaps showing the averaged extent of the infected area in Gi (C, N = 4) and in d-MdV (F, N = 4). G, H Comparison of effects of unilateral activation of CaMKIIa-RNs in MdV-IRt, in d-MdV, and in Gi area on the head (G) and trunk (H) roll tilt in animals standing on a horizontal surface. In G and H, mean ± SD values of the difference between two conditions (unilateral activation and control) are shown. In G, H: N = 7 for MdV-IRt, N = 4 for Gi, and N = 4 for d-MdV.

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