Fig. 1

Design concept and structural features of the nanocube. a A photo of a mortise and a tenon, or Hozo, which is traditionally used in Japan for making furniture without the use of nails and glue. b A concept of molecular Hozo toward supramolecular structures constructed without directional molecular interactions. The hydrating water molecules on both faces of the GSA are omitted for clarity. c The nanocube contains a C3 axis and has point symmetry, belonging to the S6 point group. d Molecular structure of BM nanocube. e The nanocube has about a 1-nm-sized inner space, which can be filled with hydrophobic molecules (G)