Fig. 1
From: Stereochemical conversion of nucleic acid circuits via strand displacement
Molecular components for stereochemical conversion. a Chemical structures of the right-handed (RH), left-handed (LH), and non-helical (NH) PNA conformers. B = nucleobases (A, C, G, T). b Strand displacement reactions involving a contiguous template strand (top) and a template strand containing a PEG-spacer (bottom). c The predicted helical sense and conformational state of molecular converters containing a contiguous template strand (left) and a template strand containing a PEG-spacer (right). d Chemical compositions of TS, DS, and IS. DNA oligonucleotides D1, D2, and D3 were included for comparison. TS, template strand (15-nts), DS, displacement strand (10-nts), and IS, invading strand (15-nts). e Chemical structures of glutamic acid residue (Glu), pyrene (Pyr), and PEG-spacer
