Fig. 2

4,6-Trisubstituted-N-heterocycles by CMPS catalysis. Products observed (in black) on incubation of 4,4-dimethyl-l-GHP (a) and C-4 epimeric 4-methyl-l-GHP (b, c) with C-2 epimeric alkylmalonyl-CoA starting materials (in grey boxes). Structures of potential products not detected by LC–MS and NMR analyses are in grey