Fig. 1: Schematic illustration of the experimental system.
From: Induction of retinopathy by fibrillar oxalate assemblies
a Abnormal electroretinography (ERG) responses were observed in patients in the absence of crystal deposition retinopathy. b Formation of an alternative organization of oxalate supramolecular structures in vitro. Fibrillary nano-assemblies were formed along the interface of separated oxalate supersaturated solution, as determined by transmission electron microscopy (TEM). c The non-canonical structures inflicted cytotoxicity in retinal pigment epithelium (RPE) cell line. d Injection of the oxalate fibrils resulted in diminished ERG responses in treated rat eyes, but not in the corresponding control eyes.
