Fig. 5: Experimental analysis of CATCH co-assembly kinetics. | Communications Chemistry

Fig. 5: Experimental analysis of CATCH co-assembly kinetics.

From: Charge guides pathway selection in β-sheet fibrillizing peptide co-assembly

Fig. 5

a CD kinetic spectra of CATCH(4+/4−) and CATCH(6+/6−) co-assemblies over time at 400 µM (t = 0, dashed black line; t = 10 min, solid light gray line; t = 30 min, solid dark gray line; t = 60 min, solid black line). b Thioflavin T kinetic measurements of CATCH(4+) (blue triangles), CATCH(4−) (red squares), CATCH(4+/4−) (black circles), CATCH(6+) (blue triangles), CATCH(6−) (red squares), and CATCH(6+/6−) (black circles) at 500 µM, error bars shown as the standard error of the mean. c TEM of 10 µM CATCH(4+/4−) and CATCH(6+/6−) at 1, 10, and 60 min (scale bar = 200 nm).

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