Fig. 6: RMs for guest encapsulation and controlled release.
From: Design, synthesis and applications of responsive macrocycles

a the chemical structure of bent-shaped aromatic ligand, the self-assembly process under reversible acid/base-induced isomerization to form hexameric macrocycle 19 from dimeric disk and the further morphology changing process from right-handed solid fibers to left-handed hollow tubules67. b the chemical structure of the macrocycle 20 and the representation of hypoxia-responsive imaging mechanism68. c the chemical structure of the macrocycle 21, the disassembly and further drug release process of the formed nanotubes after protonation of pyridyl site during the environmental pH changes70.