Fig. 8: SRMs for controlling the properties of bioactive substance.
From: Design, synthesis and applications of responsive macrocycles

a the chemical structure and switchable cytotoxicity of DAE-based peptidomimetic macrocycle 24 during the reversible photoisomerization76. b photoswitched helical structure of azo-based cyclic peptide 25 and the further self-assemble into multimeric α-helical aggregates for enhancing cell penetration78.