Fig. 5: FIH binds peptides with different substrate residues in a similar overall manner. | Communications Chemistry

Fig. 5: FIH binds peptides with different substrate residues in a similar overall manner.

From: A human protein hydroxylase that accepts D-residues

Fig. 5

Ribbons representation of superimposed peptide substrates when bound to FIH as observed by X-ray crystallography (violet); orange, (L)-leucine (PDB: 4B7E); yellow-green, (D)-leucine CA substrate (PDB: 4JAA); maroon, (2R,3S) C3 hydroxyleucine CA substrate (PDB: 6RUJ); purple, (D)-allylglycine CA substrate (PDB: 4NR1). The active site metal is a turquoise sphere. Note only one monomer of the FIH dimer is shown.

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