Fig. 2: Inhibitory potency of FIIN-2, TAS-120 and PRN1371 against FGFRs. | Communications Chemistry

Fig. 2: Inhibitory potency of FIIN-2, TAS-120 and PRN1371 against FGFRs.

From: Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors

Fig. 2

The kinase assays of inhibitors FIIN-2 (black circles), TAS-120 (red diamonds) and PRN1371 (blue triangles) against FGFR1 (a), FGFR2 (b), FGFR3 (c), FGFR4 (d) were analyzed using an in vitro kinase assay kit as described in the Materials and Methods. Data are represented as mean of n = 3 independent experiments.

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