Fig. 3: Inhibitory potency of FIIN-2, TAS-120 and PRN1371 against SFKs.
From: Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors
The kinase assays of inhibitors FIIN-2 (black circles), TAS-120 (red diamonds) and PRN1371 (blue triangles) against SRC (a), YES (b), SRC(C277A) (c) and HCK (d) were performed using an in vitro kinase assay kit as described in the Materials and Methods. Data are represented as mean of n = 3 independent experiments.
