Fig. 6: Structural models of FGFR1 gatekeeper mutants with PRN1371.
From: Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors

Docking model of PRN1371 to FGFR1(WT) (a), FGFR1(V561M) (b) and FGFR1(V561F) (c). Molecular docking was performed by AutoDock Tools program.