Table 2 Predicted binding energies of FGFR1 gatekeeper mutants with PRN1371.
From: Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors
| Â | WT | V561M | V561F |
|---|---|---|---|
Predicted Binding Energy (Kcal·mol−1) | −9.3 | −9.0 | −3.3 |
From: Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors
| Â | WT | V561M | V561F |
|---|---|---|---|
Predicted Binding Energy (Kcal·mol−1) | −9.3 | −9.0 | −3.3 |
