Fig. 2: Reaction scope of O-directed borylation of terminal alkenes. | Communications Chemistry

Fig. 2: Reaction scope of O-directed borylation of terminal alkenes.

From: A practical preparation of bicyclic boronates via metal-free heteroatom-directed alkenyl sp2-C‒H borylation

Fig. 2

aReactions were performed with 1 (0.2 mmol), 2a (1.1 equiv, 1.0 M in DCM), A5 (1.1 equiv) in DCM (1.0 mL) under N2 atmosphere, –60 °C. bYield of isolated product. c2a (3.0 equiv, 1.0 M in DCM), A5 (1.1 equiv), –60 °C. d2a (2.0 equiv, 1.0 M in DCM), A5 (2.0 equiv), –60 °C. eA5 (2.0 equiv), –40 °C, 12 h. f2a (10.0 equiv, 1.0 M in DCM), A5 (10.0 equiv), 0 °C, 8 h. g2a (2.0 equiv, 1.0 M in DCM), A5 (2.0 equiv), 0 °C.

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