Fig. 6: Identification of the composition of commercially available medicinal grade GM1 using the MOCECA strategy. | Communications Chemistry

Fig. 6: Identification of the composition of commercially available medicinal grade GM1 using the MOCECA strategy.

From: A modular chemoenzymatic cascade strategy for the structure-customized assembly of ganglioside analogs

Fig. 6

a HRMS spectrum for a commercial GM1 drug named Sygen™. b HRMS spectrum for glycosphingosine products of MOCECA-synthesized GM1 analogs mixed with GM1 (d18:1/C18:0) and GM1 (d20:1/C18:0) hydrolyzed by SA_SCD. c HRMS spectrum for glycosphingosine products of MOCECA-synthesized GM1 analogs mixed with GM1 (d18:1/C18:0) and GM1 (d18:1/C20:0) hydrolyzed by SA_SCD. d HRMS spectrum for glycosphingosine products of Sygen™ hydrolyzed by SA_SCD.

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