Fig. 1: Multivalency-driven all-DNA coacervates: coacervate preparation, switching, autonomous behavior, and engineered wetting for multiphase structures.
From: A facile DNA coacervate platform for engineering wetting, engulfment, fusion and transient behavior
DNA coacervates are prepared via multivalency-driven liquid–liquid phase separation (LLPS) between a ssDNA polymer (polyA) and shorter self-complimentary binders (Bx). The introduction of DNA or RNA invaders triggers the formation of switchable and transient coacervates. Using two distinct coacervates with different palindromic domains allows controlling multiphase structures through engineering wetting.
