Fig. 1: Proposed mechanism for the formation of nanoparticle assemblies in helium droplets by using a molecular template.
From: Precision engineering of nano-assemblies in superfluid helium by the use of van der Waals forces

As helium droplets travel in the vacuum through sample cells, they first acquire a molecular template (a diol molecule in this illustration) and then metal atoms to form nanoparticles on specific binding sites of the templates.