Fig. 3: Substrate scope study for synthesis of furazans 3. | Communications Chemistry

Fig. 3: Substrate scope study for synthesis of furazans 3.

From: Preparation of a benziodazole-type iodine(III) compound and its application as a nitrating reagent for synthesis of furazans via a copper-catalyzed cascade process

Fig. 3

[a] Reaction conditions: enamine 2 (0.3 mmol, 1.0 equiv), O2NO-I(III) 1d (0.45 mmol, 1.5 equiv), CuI (10% mol) in acetonitrile (4 mL) under N2 atmosphere at 60 °C for 6 h. [b] Isolated yield. [c] Gram-scale synthesis of 3a, 67% (10 mmol of 2a was used).

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