Scheme 2: Substrate scope. | Communications Chemistry

Scheme 2: Substrate scope.

From: Feedstock chemical dichloromethane as the C1 source for the chemoselective multicomponent synthesis of valuable 1,4,2-dioxazoles

Scheme 2

aReaction conditions: 1 (0.2 mmol), 2 (0.5 mmol) and DBU (0.5 mmol) in DCM (2 mL) at 60 °C for 24 h under argon. Isolated yields are reported. b4, 5: r.r. = 1:1.3; 6: r.r. = 1:1; 7, 8: r.r. = 1:1.1; cAt 80 °C in DCM (1 mL) and CH3CN (3 mL). dAt 80 °C in DCM (1 mL) and dioxane (3 mL).

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