Table 4 Melting temperatures for loop-substituted aPP analogs derived from variable temperature °C

From: Stabilization of a miniprotein fold by an unpuckered proline surrogate

Peptide

Substitution

Tm (°C)

7

none (wt)

54.2 ± 0.1

19

ΔaPro13

61.2 ± 1.4

20

Ala13

49.5 ± 2.0

21

ΔaPro4/6/13

61.6 ± 0.7

  1. Values represent the mean and standard deviation from 2 separate thermal denaturation experiments.