Table 4 Melting temperatures for loop-substituted aPP analogs derived from variable temperature °C
From: Stabilization of a miniprotein fold by an unpuckered proline surrogate
Peptide | Substitution | Tm (°C) |
---|---|---|
7 | none (wt) | 54.2 ± 0.1 |
19 | ΔaPro13 | 61.2 ± 1.4 |
20 | Ala13 | 49.5 ± 2.0 |
21 | ΔaPro4/6/13 | 61.6 ± 0.7 |