Table 4 Torsion angles of the backbone in the structure of 2′,3′-trans-BNAs shown in Fig. 5

From: Synthesis and structural analysis of dinucleotides containing 2′,3′-trans-bridged nucleic acids with trans-5,6- or 5,7-fused ring skeleton

 

Torsion angle (°)

 

δ

ε

ζ

α

β

RNA duplex (A type)83

81 ± 7

−157 ± 12

−71 ± 12

−67 ± 17

174 ± 14

DNA duplex (B type)83

128 ± 13

−176 ± 11

−95 ± 10

−62 ± 15

176 ± 9

2′,3′-5,6-trans-BNAolefin (23a)

85

163

−16

176

–

2′,3′-5,6-trans-BNA (24a)

83

175

−55

172

–

2′,3′-5,7-trans-BNA (28a, R-isomer)

85

−169

−59

69

159

2′,3′-5,7-trans-BNA (29a, S-isomer)

83

158

29

−79

−170

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