Table 1 Summarized data of the precursor polymer and the SCNPs: average number of pyrrole units per chain, PPy content in the SCNP, apparent number average molecular weight Mnapp, degree of compaction G after single-chain collapse, polydispersity index Ð, hydrodynamic diameter Dh, cloud point temperature Tcp, and mass extinction coefficient ε

From: Photo-thermoresponsive polypyrrole-crosslinked single-chain nanoparticles for photothermal therapy

 

average number of Py units per chain

PPy content (µg mg-1)

Mnapp a (kDa)

G b (%)

Ð

Dh c (nm)

Tcpd (°C)

ε (722 nm)e (mL mg-1 cm-1)

ε (815 nm)e (mL mg-1 cm-1)

Polymer

8.5

—

25.0

—

1.47

9.42 ± 0.05

49.5

—

—

SCNP0

8.5

22.8

14.2

43.2

1.25

8.2 ± 0.1

49.4

0.14

0.18

SCNP2

25.5

65.4

14.2

43.2

1.38

8.4 ± 0.5

50.3

1.53

1.04

SCNP5

51.0

122.9

13.1

47.6

1.30

8.9 ± 0.6

49.5

3.51

2.52

SCNP10

93.5

204.2

11.9

52.4

1.34

6.8 ± 0.6

52.9

15.31

14.25

  1. a Measured by GPC in THF.
  2. b Compaction factor G calculated with G = 100 (Mn,Polymer - Mn,SCNPapp)/Mn,Polymer.
  3. c Measured by DOSY-NMR in D2O at concentrations of 1 mg mL-1, calculated using Dh = (kB ∙ T) / (3 ∙ π ∙ η ∙ D).
  4. d Measured by turbidimetry at concentrations of 1 mg mL-1, Tcp = T at 90% transmittance, see Fig. 1d. Error is ±0.2 °C, after statistical analysis e Based on the total mass of pyrrole in the system.
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