Fig. 2: OrbiSIMS depth profiles of different component fragment ions in Formulation 1.

a DSPC, b Dlin-MC3-DMA and c Cholesterol. The intensity has been normalised to total ion count and the ions: C5H6N5+, C6H12NO2+, C37H67+ and C27H45+ are presented on secondary intensity scale (indicated by arrows) for clarity due to the difference in overall peak intensities.