Fig. 5: Photoreaction mechanism of photocages taking BW3MP as an example.
From: Hydrazone-based photocages for precise sub-organelle visualization and drug release
a Mass spectra peak area under air environments and oxygen-free environment, b Relative ROS levels of BW3MP (100 μM in DMSO, detected by fluorescence intensity of DCFH-DA fluorescent probe) with irradiation and non-irradiation, c Electron density of BW3MP, d The proposed uncaging mechanism for BW3MP, e Comparison of 1H NMR changes in BW3MP (1.5 mM in DMSO) during photodegradation with 1H NMR of BWA and MP. f EIC analysis of BW3MP and its uncaged products under different irradiation times, g Conversion rate of BW3MP, MP release rate was 75.5%.
