Fig. 3: Characterisation of age-related changes in the condensate morphology. | Communications Chemistry

Fig. 3: Characterisation of age-related changes in the condensate morphology.

From: Nanoscale profiling of evolving intermolecular interactions in ageing FUS condensates

Fig. 3

ae The morphology of condensates was measured via AFM as a function of the ageing time (ta). Z-scale bar is in nanometres. f Single condensate statistical analysis was performed on AFM images to determine change in height as a function of ageing time. Mean heights and SD: 0 h 15 ± 14 nm, n = 224 condensates from 3 sample preparations; 2 h, 31 ± 15 nm, n = 101; 4 h, 42 ± 18 nm, n = 104; 8 h, 42 ± 15 nm, n = 105; 24 h, 48 ± 20 nm, n = 62. ns not significant, *p < 0.05, one-sided t test. Box represents 25, 75 percentile and whiskers represent SD.

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