Fig. 5: Local increase in contractility can both initiate and arrest migration.
From: Optogenetic control of migration of contractile cells predicted by an active gel model
a Motility can be initiated by optogenetically perturbing the flat motor concentration in (the left) half of the cell; activation \({{{{{{{\mathcal{E}}}}}}}}/{{{{{{{\mathcal{P}}}}}}}}=1.2 \% ,0.8 \%\) for A, B. b Motility can be arrested or reoriented when a motile steady state is activated in the leading (right) half; activation \({{{{{{{\mathcal{E}}}}}}}}/{{{{{{{\mathcal{P}}}}}}}}=6.7 \% ,6.6 \% ,4 \%\) for A, B, and C. Solid curves are simulations and dashed (dotted) lines represent stable (unstable) steady states; motile (non-motile) states are in gray (black). Time periods of activation are shaded.
