Table 1 Characteristics of the 178 patients of the Outcomerea database
From: Limited applicability of a COVID-19 specific mortality prediction rule to the intensive care setting
Characteristicsa | N = 178 patients |
---|---|
Age | 61 [52; 69] |
Sex (Male) | 143 (80.4) |
Body mass index (kg cm−2) | 28.8 [25.6; 32.4] |
Comorbidities | |
At least one comorbidity | 113 (63.4) |
Charlson score | 1 [0; 3] |
Liver | 6 (3.4) |
Cardiovascular | 50 (28) |
Respiratory | 23 (13) |
Kidney | 22 (12.4) |
Immunosuppression | 27 (15.2) |
Symptoms on onset | |
Fever | 144 (80.8) |
Cough | 112 (63) |
Fatigue | 77 (43.2) |
Dyspnoea | 132 (74.2) |
Diarrhoea | 33 (18.6) |
Chest distress | 16 (9) |
Anosmia | 12 (6.8) |
Arthralgia | 17 (9.6) |
Time from first symptoms to ICU admission (days) | 10 [7; 12] |
Time from hospital to ICU admission (days) | 2 [1; 3] |
Laboratory test on admission | |
Neutrophils (×109 l−1) | 5,950 [4,000; 9,200] |
Lymphocytes (×109 l−1) | 800 [580; 1,110] |
Lymphocytes (%) | 9.6 [6.2; 15] |
High-sensitivity CRP (mg l−1) | 165.6 [92.4; 223] |
Ferritin (µg l−1) | 1,213 [745; 2,008.8] |
D-dimers (µg l−1) | 1,300 [741; 3,706.8] |
LDH (Ui l−1) | 453 [352; 603] |
Severity on admission | |
T > 39 °C | 68 (38.2) |
Simplified Acute Physiology Score II | 33.6 [25; 47] |
Sepsis-related Organ Failure Assessment score | 5 [4; 8] |
Norepinephrine on admission | 62 (34.8) |
Glasgow Coma Scale < 15 | 37 (20.8) |
Invasive mechanical ventilation on admission | 83 (46.6) |
PaO2/FiO2 | 179.2 [131.6; 243.6] |
PaO2/FiO2 < 200 (ratio of arterial oxygen partial pressure (PaO2 in mmHg) to fractional inspired oxygen (FiO2)) | 157(88%) |
Treatments on admission | |
Lopinavir/ritonavir | 72 (40.4) |
Hydroxychloroquine | 21 (11.8) |
Corticosteroids | 69 (38.8) |
During ICU stay | |
Invasive mechanical ventilation during ICU stay | 115 (64.6) |
Any nosocomial infection | 60 (33.8) |
Bacteremia | 35 (19.6) |
Hospital-acquired and ventilator-associated pneumonia | 54 (30.4) |
Outcomes | |
ICU ventilatory free days | 3 [1; 7] |
ICU length of stay | 11 [6; 19] |
ICU death | 58 (32.6) |
Mortality at day 60 | 62 (34.8) |